Metabolic crosstalk
نویسندگان
چکیده
منابع مشابه
Crosstalk between metabolic and neuropsychiatric disorders
Evidence supporting the concurrence of metabolic disturbances (e.g. insulin resistance, diabetes and obesity) and neuropsychiatric disorders has been demonstrated in both human and animal studies, suggesting the possibility that they have shared pathophysiological mechanisms. During the past decade, our understanding for the role of insulin in both normal and abnormal central nervous system (CN...
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To enhance the understanding of cells’ response in a specific condition, one requires information that shows the interconnected view of biological process. Broadly speaking, biological pathways fall into two functional categories: metabolic and regulatory pathways. Existing pathway databases are categorizing specific pathway types according to their own definition about their own subject. They ...
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The metabolic network has a modular architecture, is robust to perturbations, and responds to biological stimuli and environmental conditions. Through monitoring by metabolite responsive macromolecules, metabolic pathways interact with the transcriptome and proteome. Whereas pathway interconnecting cofactors and substrates report on the overall state of the network, specialised intermediates me...
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1 Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125 Torino, Italy 2 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, 84103 Beer-Sheva, Israel 3 Division of Paediatric Endocrinology and Diabetology, University Children’s Hospital, ...
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Obstructive sleep apnoea (OSA) is a prevalent sleep disorder characterized by upper airway obstruction during sleep, resulting in intermittent breathing pauses despite effort, reduced blood oxygen saturation, hypoxia and arousals. With prevalence in the general population estimated at 17–24% of men and 5–9% of women (Young et al. 1993; Bixler et al. 1998, 2001), OSA has been linked to the key c...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2018
ISSN: 1529-2908,1529-2916
DOI: 10.1038/s41590-018-0268-y